La maladie de Parkinson au Canada (serveur d'exploration)

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Unique form of propriospinal myoclonus as a possible complication of an enteropathogenic toxin

Identifieur interne : 002E14 ( Main/Exploration ); précédent : 002E13; suivant : 002E15

Unique form of propriospinal myoclonus as a possible complication of an enteropathogenic toxin

Auteurs : Alberto J. Espay [Canada] ; Peter Ashby [Canada] ; Ritsuko Hanajima [Canada] ; Mandar S. Jog [Canada] ; Anthony E. Lang [Canada]

Source :

RBID : ISTEX:79B050646C3007534823AC0FE14C9105B2A16B90

English descriptors

Abstract

Propriospinal myoclonus is an uncommon form of spinal myoclonus propagated, presumably, by slowly conducting polysynaptic intraspinal pathways. Although most patients demonstrate no clear etiology, a variety of disorders have been linked to this abnormal movement, including trauma, multiple sclerosis, tumors, and infectious disorders such as herpes zoster, human immunodeficiency virus, and Lyme disease. We describe 2 young male patients from the same town in Northern Ontario, Canada, exposed to an outbreak of Escherichia coli O157:H7 from contaminated municipal water, who developed identical clinical and electrophysiological features suggestive of a rhythmic form of propriospinal myoclonus with activity alternating between abdominal and paraspinal muscles. A toxin‐mediated microvascular thrombosis is proposed as a possible pathogenic mechanism underlying this novel association. © 2003 Movement Disorder Society

Url:
DOI: 10.1002/mds.10453


Affiliations:


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Le document en format XML

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